张美春，医学博士，副研究员，江苏省血吸虫病防治研究所青年PI。主要从事蚊媒传染病防控技术研究。先后主持国家自然科学基金、广东省自然科学基金、国家自然科学基金委员会与盖茨基金会全球健康合作研究项目子课题和“滨湖之光”创新领军人才计划项目等科研项目，发表论文20余篇。

教育经历：

2005/09-2011/07 中山大学   病原生物学   博士   

2000/09-2005/07 安徽中医药大学  中西医结合临床医学  学士

工作经历：

2024/03-至今  江苏省血吸虫病防治研究所  副研究员

2019/12-2023/05 密歇根州立大学(Michigan State University)         博士后

2016/10-2019/10  中山大学  特聘副研究员

2011/07-2016/07 六安市人民医院  主管检验师

一、部分论文发表情况

(1) Meichun Zhang, Han Wen, Qiang Sun, Dongjing Zhang, Yongjun Li, Andrew Xi, Xiaoying Zheng, Yu Wu, Jun Cao, Jeremy Bouyer, and Zhiyong Xi*. Early 20-hydroxyecdysone threshold attainment in male shapes sexual dimorphism in mosquito development. Nature Communications, 2025, 16(1): 821.

(2) Si-jia Deng#, Lei Tu#, Lin Li, Ju-ping Hu, Ju-lin Li, Jian-xia Tang, Mei-chun Zhang*, Guo-ding Zhu*, Jun Cao*. A symbiotic bacterium regulates the detoxification metabolism of deltamethrin in Aedes albopictus. Pesticide Biochemistry and Physiology, 2025, 212: 106445.

(3) Dongjing Zhang, Zhiyong Xi, Yongjun Li, Xiaohua Wang, Hanano Yamada, Jieru Qiu, Yongkang Liang, Meichun Zhang*, Yu Wu*, Xiaoying Zheng*. Toward implementation of combined incompatible and sterile insect techniques for mosquito control: Optimized chilling conditions for handling Aedes albopictus male adults prior to release. PLoS Neglected Tropical Diseases, 2020, 14(9): e0008561.

(4) Meichun Zhang#, Dongjing Zhang#, Yongjun Li, Qiang Sun, Qin Li, Yali Fan, Yu Wu, Zhiyong Xi* and Xiaoying Zheng*. Water-induced strong protection against acute exposure to low subzero temperature of adult Aedes albopictus. PLoS Neglected Tropical Diseases, 2019, 13(2): e0007139.

(5) Dongjing Zhang#, Meichun Zhang#, Yu Wu, Jeremie R. L. Gilles, Hanano Yamada, Zhongdao Wu, Zhiyong Xi and Xiaoying Zheng*. Establishment of a medium-scale mosquito facility: optimization of the larval mass-rearing unit for Aedes albopictus (Diptera: Culicidae). Parasites & Vectors, 2017, 10:569.

(6) Rongrong Zhai#, Meichun Zhang#,*, Jie Liu, Hui Guang, Benzhong Li, Dong Chen, Songtao Zhang. Reference intervals of and relationships among essential trace elements in whole blood of children aged 0-14 years. Journal of Clinical Laboratory Analysis, 2017, 31(2): e22043.

(7) Meichun Zhang#,*, Shengfang Guang#, Rongrong Zhai, Jie Liu, Hui Guang，Dong Chen, Benzhong Li, Songtao Zhang. The blood lead levels of outpatients aged 1-18 years from Lu'an, China, 2012-2014. Journal of Trace Elements in Medicine and Biology, 2016, 33: 48-53.

(8) Meichun Zhang*, Rongrong Zhai, Jie Liu, Hui Guang, Benzhong Li, Dong Chen. Seasonal variation of whole blood copper levels in children aged 0-14 years. British Journal of Biomedical Science, 2016, 73(3): 147-149.

(9) Meichun Zhang*, Rongrong Zhai, Jie Liu, Hui Guang, Benzhong Li, Songtao Zhang. Seasonal Variation of Blood Calcium Levels in Children Aged 1-10. Journal of Clinical Laboratory Analysis, 2016, 30(5): 741-744.

(10) Meichun Zhang, Xiaoying Zheng, Yu Wu, Ming Gan, Ai He, Zhuoya Li, Dongjing Zhang, Xiansheng Wu and Ximei Zhan*. Differential proteomics of Aedes albopictus salivary gland, midgut and C6/36 cell induced by dengue virus infection. Virology, 2013, 444(1-2): 109-118.

(11) Meichun Zhang, Xiaoying Zheng, Yu Wu, Ming Gan, Ai He, Zhuoya Li, Jing Liu and Ximei Zhan*. Quantitative analysis of replication and tropisms of dengue virus type 2 in Aedes albopictus. American Journal of Tropical Medicine and Hygiene, 2010, 83(3): 700-707.

二、论著章节

Meichun Zhang and Zhiyong Xi*. Wolbachia transinfection via embryonic microinjection. Ann Fallon (ed.), Wolbachia: Methods and Protocols, Methods in Molecular Biology, 2023, vol. 2739, 2024: 175-188. DOI: 10.1007/978-1-0716-3553-7_11.

三、专利情况

Zhiyong Xi, Meichun Zhang. Homogenization method of infecting a mosquito with wolbachia. Patent No.: US12022813B2. 07/02/2024

四、承担科研项目情况

1. 国家自然科学基金委-盖茨基金会全球健康联合资助项目 新型沃尔巴克氏菌户外按蚊控制技术的规模化实施与疟疾传播阻断研究，82561128255/2025MVIP0104，2026.01-2028.12，参与（子课题负责人）

2. 国家自然科学基金-青年科学金项目 白纹伊蚊体内ROS调控登革病毒感染水平的分子机制研究，81702033，2018.01-2020.12，已结题，主持

3. 广东省自然科学基金-面上项目 Hsp70蛋白在白纹伊蚊抗登革病毒感染免疫过程中的作用及其机制研究，2017A030313523，2017.05-2020.05，已结题，主持